{ "_id": "6a2272c3cd65a98ecbd49a38", "Package": "IMIX", "Type": "Package", "Version": "1.1.5", "Date": "2022-07-13", "Title": "Gaussian Mixture Model for Multi-Omics Data Integration", "Authors@R": "c(person(\"Ziqiao\",\"Wang\",role=c(\"aut\",\"cre\"),email=\"wzqjanet@gmail.com\",comment = c(ORCID = \"0000-0003-3383-8670\")),person(\"Peng\",\"Wei\",role=c(\"ths\"),email=\"pwei2@mdanderson.org\",comment = c(ORCID = \"0000-0001-7758-6116\")))", "Description": "A multivariate Gaussian mixture model framework to\nintegrate multiple types of genomic data and allow modeling of\ninter-data-type correlations for association analysis. 'IMIX'\ncan be implemented to test whether a disease is associated with\ngenes in multiple genomic data types, such as DNA methylation,\ncopy number variation, gene expression, etc. It can also study\nthe integration of multiple pathways. 'IMIX' uses the summary\nstatistics of association test outputs and conduct integration\nanalysis for two or three types of genomics data. 'IMIX'\nfeatures statistically-principled model selection, global FDR\ncontrol and computational efficiency. Details are described in\nZiqiao Wang and Peng Wei (2020)\n.", "License": "GPL-2", "Encoding": "UTF-8", "LazyData": "true", "URL": "https://github.com/ziqiaow/IMIX", "BugReports": "https://github.com/ziqiaow/IMIX/issues", "RoxygenNote": "7.1.1", "NeedsCompilation": "no", "Author": "Ziqiao Wang [aut, cre]\n(), Peng Wei [ths]\n()", "Maintainer": "Ziqiao Wang ", "Config/pak/sysreqs": "cmake make libicu-dev libuv1-dev libssl-dev", "Repository": "https://ziqiaow.r-universe.dev", "Date/Publication": "2026-04-06 18:29:56 UTC", "RemoteUrl": "https://github.com/ziqiaow/imix", "RemoteRef": "HEAD", "RemoteSha": "d8b57fdb66d74e28326551fb1edde1d0c9fb105c", "Packaged": { "Date": "2026-06-05 06:50:30 UTC", "User": "root" }, "MD5sum": "9403bda029433edc0f12c5d861050cd1", "_user": "ziqiaow", "_type": "src", "_file": "IMIX_1.1.5.tar.gz", "_fileid": "f294d30cb02f0caeab83ac65fd00a0adef82de4da3a6f68558df885282f2c1ae", "_filesize": 1132524, "_sha256": "f294d30cb02f0caeab83ac65fd00a0adef82de4da3a6f68558df885282f2c1ae", "_created": "2026-06-05T06:50:30.000Z", "_published": "2026-06-05T06:54:59.528Z", "_distro": "noble", "_jobs": [ { "job": 79678665458, "time": 168, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "WARNING", "artifact": "7430587290" }, { "job": 79678665405, "time": 143, "config": "linux-release-x86_64", "r": "4.6.0", "check": "WARNING", "artifact": "7430581266" }, { "job": 79678665406, "time": 234, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "WARNING", "artifact": "7430593173" }, { "job": 79678665404, "time": 126, "config": "macos-release-arm64", "r": "4.6.0", "check": "WARNING", "artifact": "7430573210" }, { "job": 79678230013, "time": 219, "config": "source", "r": "4.6.0", "check": "OK", "artifact": "7430548171" }, { "job": 79678665402, "time": 121, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "7430576108" }, { "job": 79678665399, "time": 160, "config": "windows-devel", "r": "4.7.0", "check": "WARNING", "artifact": "7430585554" }, { "job": 79678665504, "time": 119, "config": "windows-oldrel", "r": "4.5.3", "check": "WARNING", "artifact": "7430575849" }, { "job": 79678665385, "time": 112, "config": "windows-release", "r": "4.6.0", "check": "WARNING", "artifact": "7430574175" } ], "_buildurl": "https://github.com/r-universe/ziqiaow/actions/runs/27000031735", "_status": "success", "_host": "GitHub-Actions", "_upstream": "https://github.com/ziqiaow/imix", "_commit": { "id": "d8b57fdb66d74e28326551fb1edde1d0c9fb105c", "author": "Ziqiao Wang ", "committer": "GitHub ", "message": "Add files via upload", "time": 1775500196 }, "_maintainer": { "name": "Ziqiao Wang", "email": "wzqjanet@gmail.com", "login": "ziqiaow", "orcid": "0000-0003-3383-8670", "description": "PhD in Biostatistics. My research focuses on high dimensional data analysis, polygenic risk score, integrative genomics, and mixture models.", "uuid": 59397785 }, "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 3.5", "role": "Depends" }, { "package": "crayon", "role": "Imports" }, { "package": "mvtnorm", "role": "Imports" }, { "package": "mixtools", "role": "Imports" }, { "package": "mclust", "role": "Imports" }, { "package": "ggplot2", "role": "Imports" }, { "package": "stats", "role": "Imports" }, { "package": "utils", "role": "Imports" }, { "package": "MASS", "role": "Imports" } ], "_owner": "ziqiaow", "_selfowned": true, "_usedby": 0, "_updates": [ { "week": "2026-15", "n": 2 } ], "_tags": [], "_stars": 7, "_contributors": [ { "user": "ziqiaow", "count": 77, "uuid": 59397785 } ], "_userbio": { "uuid": 59397785, "type": "user", "name": "Ziqiao Wang", "description": "PhD in Biostatistics. My research focuses on high dimensional data analysis, polygenic risk score, integrative genomics, and mixture models." }, "_downloads": { "count": 179, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/IMIX" }, "_mentions": 1, "_devurl": "https://github.com/ziqiaow/imix", "_searchresults": 0, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/IMIX.html", "extra/readme.html", "extra/readme.md", "manual.pdf" ], "_homeurl": "https://github.com/ziqiaow/imix", "_realowner": "ziqiaow", "_cranurl": true, "_releases": [ { "version": "1.1.0", "date": "2020-12-08" }, { "version": "1.1.4", "date": "2021-02-10" }, { "version": "1.1.5", "date": "2022-07-13" } ], "_exports": [ "FDR_control_adaptive", "FDR_control_adaptive_imix", "IMIX", "IMIX_cor", "IMIX_cor_restrict", "IMIX_cor_twostep", "IMIX_ind", "model_selection", "model_selection_component", "plot_component" ], "_datasets": [ { "name": "data_p", "title": "P value matrix of two data types", "object": "data_p", "class": [ "matrix", "array" ], "fields": [ "p.rnaseq", "p.cnv" ], "rows": 1000, "table": true, "tojson": true } ], "_help": [ { "page": "data_p", "title": "P value matrix of two data types", "topics": [ "data_p" ] }, { "page": "FDR_control_adaptive", "title": "The Adaptive Procedure for Across-Data-Type FDR Control", "topics": [ "FDR_control_adaptive" ] }, { "page": "FDR_control_adaptive_imix", "title": "The Adaptive Procedure for Across-Data-Type FDR Control for IMIX Output", "topics": [ "FDR_control_adaptive_imix" ] }, { "page": "IMIX", "title": "IMIX", "topics": [ "IMIX" ] }, { "page": "IMIX_cor", "title": "IMIX-Cor", "topics": [ "IMIX_cor" ] }, { "page": "IMIX_cor_restrict", "title": "IMIX-Cor-Restrict", "topics": [ "IMIX_cor_restrict" ] }, { "page": "IMIX_cor_twostep", "title": "IMIX-Cor-Twostep", "topics": [ "IMIX_cor_twostep" ] }, { "page": "IMIX_ind", "title": "IMIX-ind", "topics": [ "IMIX_ind" ] }, { "page": "model_selection", "title": "Model Selection", "topics": [ "model_selection" ] }, { "page": "model_selection_component", "title": "Component Selection", "topics": [ "model_selection_component" ] }, { "page": "plot_component", "title": "Plot the AIC or BIC Values for Model Selection", "topics": [ "plot_component" ] } ], "_readme": "https://github.com/ziqiaow/imix/raw/HEAD/README.md", "_rundeps": [ "askpass", "base64enc", "bslib", "cachem", "cli", "cpp11", "crayon", "crosstalk", "curl", "data.table", "digest", "dplyr", "evaluate", "farver", "fastmap", "fontawesome", "fs", "generics", "ggplot2", "glue", "gtable", "highr", "htmltools", "htmlwidgets", "httr", "isoband", "jquerylib", "jsonlite", "kernlab", "knitr", "labeling", "later", "lattice", "lazyeval", "lifecycle", "magrittr", "MASS", "Matrix", "mclust", "memoise", "mime", "mixtools", "mvtnorm", "nlme", "openssl", "otel", "pillar", "pkgconfig", "plotly", "promises", "purrr", "R6", "rappdirs", "RColorBrewer", "Rcpp", "rlang", "rmarkdown", "S7", "sass", "scales", "segmented", "stringi", "stringr", "survival", "sys", "tibble", "tidyr", "tidyselect", "tinytex", "utf8", "vctrs", "viridisLite", "withr", "xfun", "yaml" ], "_score": 3.5440680443502757, "_indexed": true, "_nocasepkg": "imix", "_universes": [ "ziqiaow" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "1.1.5", "date": "2026-06-05T06:53:09.000Z", "distro": "noble", "commit": "d8b57fdb66d74e28326551fb1edde1d0c9fb105c", "fileid": "7be5ae459237a085584c2e9ee13bc14fae7f54f6503ba723f83c31d9766dbcbb", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/ziqiaow/actions/runs/27000031735" }, { "r": "4.6.0", "os": "linux", "version": "1.1.5", "date": "2026-06-05T06:52:45.000Z", "distro": "noble", "commit": "d8b57fdb66d74e28326551fb1edde1d0c9fb105c", "fileid": "d472f45bc7cd227551b39f6ee88f4a8cd39b396d67c4a320dc3f0fc4710c8a67", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/ziqiaow/actions/runs/27000031735" }, { "r": "4.5.3", "os": "mac", "version": "1.1.5", "date": "2026-06-05T06:53:34.000Z", "commit": "d8b57fdb66d74e28326551fb1edde1d0c9fb105c", "fileid": "01655e3dab34c03c37617937747fcf7c9a13b96c5a432cae2d2405f27bbdd2c2", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/ziqiaow/actions/runs/27000031735" }, { "r": "4.6.0", "os": "mac", "version": "1.1.5", "date": "2026-06-05T06:52:19.000Z", "commit": "d8b57fdb66d74e28326551fb1edde1d0c9fb105c", "fileid": "6fdf0757ce7bb473a45c4b82ce3d0a7fef44bd8e88301441ee27779666f308bc", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/ziqiaow/actions/runs/27000031735" }, { "r": "4.6.0", "os": "wasm", "version": "1.1.5", "date": "2026-06-05T06:52:50.000Z", "commit": "d8b57fdb66d74e28326551fb1edde1d0c9fb105c", "fileid": "53359691547141fef464b7bd487a25f84df5dca7a373683ea33ff24326c85d1d", "status": "success", "buildurl": "https://github.com/r-universe/ziqiaow/actions/runs/27000031735" }, { "r": "4.7.0", "os": "win", "version": "1.1.5", "date": "2026-06-05T06:52:33.000Z", "commit": "d8b57fdb66d74e28326551fb1edde1d0c9fb105c", "fileid": "b64bbc1b8c9aee8061c6aaaed25396ba68eb43a36ba5be8471b740acc3a975a1", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/ziqiaow/actions/runs/27000031735" }, { "r": "4.5.3", "os": "win", "version": "1.1.5", "date": "2026-06-05T06:52:11.000Z", "commit": "d8b57fdb66d74e28326551fb1edde1d0c9fb105c", "fileid": "ea297ca4619f2aca8699ac2830b22eece63af5c0359742d4f27f35a31659eca8", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/ziqiaow/actions/runs/27000031735" }, { "r": "4.6.0", "os": "win", "version": "1.1.5", "date": "2026-06-05T06:52:03.000Z", "commit": "d8b57fdb66d74e28326551fb1edde1d0c9fb105c", "fileid": "cd780af6b76344fde31ffda11d57a92a5a55939b0f22ececfb83dc78df6bd5ef", "status": "success", "check": "WARNING", "buildurl": "https://github.com/r-universe/ziqiaow/actions/runs/27000031735" } ] }