Package: IMIX 1.1.5

IMIX: Gaussian Mixture Model for Multi-Omics Data Integration

A multivariate Gaussian mixture model framework to integrate multiple types of genomic data and allow modeling of inter-data-type correlations for association analysis. 'IMIX' can be implemented to test whether a disease is associated with genes in multiple genomic data types, such as DNA methylation, copy number variation, gene expression, etc. It can also study the integration of multiple pathways. 'IMIX' uses the summary statistics of association test outputs and conduct integration analysis for two or three types of genomics data. 'IMIX' features statistically-principled model selection, global FDR control and computational efficiency. Details are described in Ziqiao Wang and Peng Wei (2020) <doi:10.1093/bioinformatics/btaa1001>.

Authors:Ziqiao Wang [aut, cre], Peng Wei [ths]

IMIX_1.1.5.tar.gz
IMIX_1.1.5.zip(r-4.7-any)IMIX_1.1.5.zip(r-4.6-any)IMIX_1.1.5.zip(r-4.5-any)
IMIX_1.1.5.tgz(r-4.6-any)IMIX_1.1.5.tgz(r-4.5-any)
IMIX_1.1.5.tar.gz(r-4.7-any)IMIX_1.1.5.tar.gz(r-4.6-any)
IMIX_1.1.5.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION
card.svg |card.png
IMIX/json (API)

# Install 'IMIX' in R:
install.packages('IMIX', repos = c('https://ziqiaow.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/ziqiaow/imix/issues

Datasets:
  • data_p - P value matrix of two data types

On CRAN:

Conda:

3.54 score 7 stars 330 downloads 1 mentions 10 exports 75 dependencies

Last updated from:d8b57fdb66. Checks:7 WARNING, 2 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-develWARNING138
source / vignettesOK194
linux-releaseWARNING139
macos-releaseWARNING203
macos-oldrelWARNING163
windows-develWARNING94
windows-releaseWARNING113
windows-oldrelWARNING97
wasm-releaseOK109

Exports:FDR_control_adaptiveFDR_control_adaptive_imixIMIXIMIX_corIMIX_cor_restrictIMIX_cor_twostepIMIX_indmodel_selectionmodel_selection_componentplot_component

Dependencies:askpassbase64encbslibcachemclicpp11crayoncrosstalkcurldata.tabledigestdplyrevaluatefarverfastmapfontawesomefsgenericsggplot2gluegtablehighrhtmltoolshtmlwidgetshttrisobandjquerylibjsonlitekernlabknitrlabelinglaterlatticelazyevallifecyclemagrittrMASSMatrixmclustmemoisemimemixtoolsmvtnormnlmeopensslotelpillarpkgconfigplotlypromisespurrrR6rappdirsRColorBrewerRcpprlangrmarkdownS7sassscalessegmentedstringistringrsurvivalsystibbletidyrtidyselecttinytexutf8vctrsviridisLitewithrxfunyaml